Smokers Light Up Less, Alternative Nicotine Delivery Technologies Take Center Stage

NetworkNewsWire Editorial Coverage: American smokers are stubbing out their cigarettes. Data from the Centers for Disease Control and Prevention (CDC) show that the proportion of the adult American population that has smoked at least 100 cigarettes during their lifetimes stood at 15.5 percent in 2016, down from 20.9 percent in 2005 (http://nnw.fm/J6dQp). Of course, quitting smoking does not always mean saying no to nicotine. The stimulant, credited with some health benefits, is highly addictive. As a result, alternative delivery biotechnologies for nicotine have become a recent R&D focus for cigarette manufacturers and other companies, including Lexaria Bioscience Corp. (CSE: LXX) (OTCQX: LXRP) (LXRP Profile), Altria Group, Inc. (NYSE: MO), British American Tobacco (NYSE: BTI), Imperial Brands (LON: IMB) (OTCQX: IMBBY) and Philip Morris International, Inc. (NYSE: PM). With close to 38 million American smokers still puffing away, and nearly 1 billion worldwide, these companies are developing safer products and delivery technologies, which may wean smokers away from a habit estimated to kill about 480,000 (1 in 5) adult Americans every year.

In the 20th Century, the average American was smoking 4,345 manufactured cigarettes per year (http://nnw.fm/k7n5A). In the early 1960s, the Surgeon General of the United States published a damning report that linked smoking to lung cancer, emphysema and heart disease, and since then the percentage of American adults who smoke has declined in every year the CDC has surveyed. Around the time of the Surgeon General’s warning in 1963, 42.4 percent of American adults smoked; 50 years later, in 2013, that rate had fallen to 21.6 percent. In 2016, it dipped even further to 15.5 percent (http://nnw.fm/Mo3wa).

Recognizing this significant downturn, paired with the fact that regardless of health risks a population of consumers will continue nicotine use, biotech innovators and even big tobacco companies are looking for ways to reduce the hazards of smoking.

The Case for Smoking Alternatives

Lexaria Bioscience Corp. (CSE: LXX) (OTCQX: LXRP) is gaining prominence for its proprietary delivery technology capable of changing the way active pharmaceutical ingredients (“APIs”) such as cannabinoids and nicotine enter the body.  The company’s DehydraTECH™ technology enables delivery of lipophilic active agents within foods, beverages, capsules and other ingestible formats, thus improving the performance of beneficial ingestible products across four categories: taste, smell, speed of action, and bioabsorption and bioavailability. DehyraTECH has already been proven effective in cannabinoid delivery and is currently undergoing testing for nicotine delivery in lab animals.

When it comes to smoking, this is of considerable importance for two reasons.

First, in 2016 a Royal College of Physicians (RCP) report concluded that “nicotine alone in the doses used by smokers represents little if any hazard to the user” – rather, it is the combination of more than 4,000 chemicals released from the combustion of tobacco that is damaging. Complementary to this finding is research by the BMJ, which shows that there is no safe level of smoking and that “only complete cessation is protective and should be emphasized by all prevention measures and policies … any exposure to cigarette smoke is too much.”

Secondly, Lexaria’s technology addresses a vital concern smoking poses to the body: human lungs were not designed to become pathways for drug absorption; their sole purpose is to deliver oxygen to the blood. Nature did, however, design an ingenious system for drug and nutrient absorption, and that method is ingestible food and drink.

Lexaria’s technology is custom-designed to work with the human gastro intestinal (GI) system to deliver APIs more effectively (DehydraTECH can deliver payload molecules to the bloodstream in as little as 10 to 15 minutes, as opposed to 60 to 90 minutes for current methods), but still respects the body’s inherent internal safety mechanisms.

Delivering minute proportions of nicotine through edible food formats like coffee or breath mints has never been successfully achieved in the past, because when detected by the GI system, nicotine is generally flushed from the intestines through cramping and GI distress.

Lexaria’s DehyraTECH technology, however, acts as a trojan horse, demonstrating potential to deliver nicotine through the GI with sharply lowered side effects.

Patented Technology is Rooted in Cannabinoids, Includes Nicotine Coverage

At present, Lexaria is the only company in the world that has been awarded patents for the improved (oral or ingestible, including pills) delivery of all cannabinoids both psychoactive and non. These patents have been awarded in the United States and Australia and are pending in 40 more countries. This puts the company in the unusually advantageous position of owning proprietary technology that can deliver a vast range of cannabinoid-based drugs.

The company recently received a new patent award in the U.S. that also protects its delivery system for use with nicotine, potentially offering the biggest disruption to nicotine delivery since the invention of the cigarette.

“Lexaria has now locked-up the IP for its next-generation drug delivery system” Lexaria CEO Chris Bunka explained in the press release (http://nnw.fm/Q8JxJ). “This ground-breaking, patented IP builds a foundation for new business opportunities in 2018 including what could be the world’s first nicotine edibles for the smokeless tobacco industry, or improved new products for NSAID-derived pain management, as well as in the rapidly growing cannabis market.”

Licensing Model in Action

Lexaria’s DehydraTECH system is being utilized in a number of consumer products developed by the company under three distinct brands: ViPova™, Lexaria Energy and TurboCBD™. In recent months, Lexaria has executed several key agreements that demonstrate the versatility of its technology and serve as examples of the company’s out-licensing model.

Most recently, Lexaria entered into a five-year licensing agreement with Biolog, Inc., in which Biolog (a Utah company, not to be confused with a California cell phenotyping company of the same name) will use DehydraTECH^TM to empower a unique set of next-generation food and beverage cannabis infusion products to be sold in the United States (http://nnw.fm/8FvlH).

In January 2018, Lexaria also announced a licensing agreement with Cannfections Group, Inc. Per the agreement, Lexaria will provide its DehydraTECH technology to enhance the performance of Cannfections’ cannabis-infused chocolates and candies to be developed and sold in Canada and internationally. The founders of Cannfections currently manufacture chocolate retail products for several leading international and domestic chocolate brands (http://nnw.fm/Ovvy7).

Tobacco Industry Potential

Rather than being a competitor to tobacco and cannabis companies, Lexaria aims to out-license its technology to third-party partners such as major cigarette manufacturers. Lexaria is expected to conduct its first in-vivo nicotine absorption tests in March and results are expected shortly thereafter. If positive, the industry could have its first data supporting a viable delivery technique for edible forms of nicotine. Tests are being conducted at a highly regarded, third-party laboratory.

Two giants in the industry, Altria Group, Inc. (NYSE: MO) and Philip Morris (NYSE: PM), are collaborating on the production and distribution of a gadget that they claim will reduce the risk of tobacco-related ailments for smokers who eschew cigarettes in favor of it. However, the partnership appears to be sailing through rough waters. A Food and Drug Administration (FDA) panel concluded almost unanimously (one abstention in the 8-0 vote) that Philip Morris had not shown that its heat-not-burn device reduces the risk of smoking-related ailments. The panel did find, however, that switching to the device, known as the iQos, reduces exposure to harmful chemicals (http://nnw.fm/xsW9F).

Meanwhile, British American Tobacco (NYSE: BTI) emphasizes the economic value of tobacco in general, but has also invested more than $1 billion into the development of Next Generation Products (“NGPs”) such as e-cigarettes and tobacco-heating products.

Without abandoning its core focus on cigarettes and other tobacco products, Imperial Brands, (LON: IMB) (OTCQX: IMBBY) is also exploring the potential of NGPs to offer smokers an alternative to combustible tobacco. “ … NGPs offer us considerable growth opportunities. We are significantly stepping up our level of NGP activity in 2018 and beyond, expanding our portfolio with new product launches in new and existing markets,” the company states on its website.

With big tobacco on board to cater to consumer trends, Lexaria occupies an interesting position in the marketplace as it continues to advance its alternative delivery system for potential out-licensing to companies like Altria, Philip Morris, British American Tobacco, Imperial Brands and others. The global tobacco industry is almost unimaginably large and orders of magnitude larger than cannabis. If proven effective, Lexaria’s technology could have the most practical and healthful application to the world’s 1 billion smokers than anything that has come before.

For more information on Lexaria, visit Lexaria Bioscience Corp. (CSE: LXX) (OTCQX: LXRP)

About NetworkNewsWire

NetworkNewsWire (NNW) is a financial news and content distribution company that provides (1) access to a network of wire services via NetworkWire to reach all target markets, industries and demographics in the most effective manner possible, (2) article and editorial syndication to 5,000+ news outlets (3), enhanced press release services to ensure maximum impact, (4) social media distribution via the Investor Brand Network (IBN) to nearly 2 million followers, (5) a full array of corporate communications solutions, and (6) a total news coverage solution with NNW Prime. As a multifaceted organization with an extensive team of contributing journalists and writers, NNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. By cutting through the overload of information in today’s market, NNW brings its clients unparalleled visibility, recognition and brand awareness. NNW is where news, content and information converge.

For more information, please visit https://www.NetworkNewsWire.com

NetworkNewsWire (NNW)
New York, New York
www.NetworkNewsWire.com
212.418.1217 Office
Editor@NetworkNewsWire.com

Please see full terms of use and disclaimers on the NetworkNewsWire website applicable to all content provided by NNW, wherever published or re-published: http://NNW.fm/Disclaimer

DISCLAIMER: NetworkNewsWire (NNW) is the source of the Article and content set forth above. References to any issuer other than the profiled issuer are intended solely to identify industry participants and do not constitute an endorsement of any issuer and do not constitute a comparison to the profiled issuer. The commentary, views and opinions expressed in this release by NNW are solely those of NNW. Readers of this Article and content agree that they cannot and will not seek to hold liable NNW for any investment decisions by their readers or subscribers. NNW is a news dissemination and financial marketing solutions provider and are NOT registered broker-dealers/analysts/investment advisers, hold no investment licenses and may NOT sell, offer to sell or offer to buy any security.

The Article and content related to the profiled company represent the personal and subjective views of the Author, and are subject to change at any time without notice. The information provided in the Article and the content has been obtained from sources which the Author believes to be reliable. However, the Author has not independently verified or otherwise investigated all such information. None of the Author, NNW, or any of their respective affiliates, guarantee the accuracy or completeness of any such information. This Article and content are not, and should not be regarded as investment advice or as a recommendation regarding any particular security or course of action; readers are strongly urged to speak with their own investment advisor and review all of the profiled issuer’s filings made with the Securities and Exchange Commission before making any investment decisions and should understand the risks associated with an investment in the profiled issuer’s securities, including, but not limited to, the complete loss of your investment.

NNW HOLDS NO SHARES OF ANY COMPANY NAMED IN THIS RELEASE.

This release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E the Securities Exchange Act of 1934, as amended and such forward-looking statements are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. “Forward-looking statements” describe future expectations, plans, results, or strategies and are generally preceded by words such as “may”, “future”, “plan” or “planned”, “will” or “should”, “expected,” “anticipates”, “draft”, “eventually” or “projected”. You are cautioned that such statements are subject to a multitude of risks and uncertainties that could cause future circumstances, events, or results to differ materially from those projected in the forward-looking statements, including the risks that actual results may differ materially from those projected in the forward-looking statements as a result of various factors, and other risks identified in a company’s annual report on Form 10-K or 10-KSB and other filings made by such company with the Securities and Exchange Commission. You should consider these factors in evaluating the forward-looking statements included herein, and not place undue reliance on such statements.  The forward-looking statements in this release are made as of the date hereof and NNW undertakes no obligation to update such statements.