Pressure BioSciences Inc. (PBIO) Announces Entry into Cannabis Marketplace with its Ultra Shear Technology Instrument Platform

• PBIO’s proprietary Ultra Shear Technology (UST) platform achieves the long sought-after ability to create truly water-soluble CBD oil that can provide optimized solubility and bioavailability for CBD absorption
• As a result of the long sought-after demand for safe and effective water-soluble CBD, the company believes that a doubling in its annual revenue run-rate over the next year is very possible, based on the sale of this totally new, proprietary instrument system; market impact includes CBD products, nutraceuticals, foods and beverages, cosmetics and other oil-based markets
• Independent, university-affiliated analytical lab test results prove that PBIO’s UST platform creates high quality, visually clear nanoemulsion mixtures of CBD oil and water and that the CBD molecule is preserved throughout the process
• The overall cannabinoid market is expected to reach $22 billion by 2022, with CBD oil-based supplements serving as a cornerstone of the booming consumer trend

Pressure BioSciences Inc. (OTCQB: PBIO), a leader in the development and sale of high pressure-based instruments, consumables and related services for the global life sciences and other industries, has just announced that its proprietary Ultra Shear Technology (UST) platform has been optimized for the unique purpose of creating high quality nanoemulsions of CBD oil in water. Independent test results have shown that these CBD oil nanoemulsions retain nearly 100 percent of the CBD molecule after processing, without altering the molecule or generating impurities. Given this new highly-effective, non-chemical ability to make truly water-soluble CBD – a solution that meets a huge long-standing need – the company announced today a major focus on the cannabis/CBD market (http://nnw.fm/Gr7D4).

UST is a novel process that has potential in a wide range of commercial applications, including extending the shelf life of some food products and making two or more insoluble liquids (like oil and water) soluble. UST is based on the use of intense shear forces generated from ultra-high-pressure valve discharge (http://nnw.fm/YwhC6). PBIO’s UST process has most recently been independently verified by chemists at NutraFuels, Inc. (OTCQB: NTFU), which has a U.S. Food and Drug Administration (“FDA”) inspected, highly qualified analytical testing laboratory with state-of-the-art equipment.

“Using a powerful laboratory method called HPLC to measure the concentrations of CBD and potential impurities, we determined that no appreciable amount of CBD was lost during the UST process,” Cooper Dodd, R&D Scientist at NTFU, stated in a news release (http://nnw.fm/Ch4SL). “These results compare well to our standard processing method of ultrasonication, which can carry a risk of measurable loss of CBD, and sometimes creates the appearance of impurities if not performed properly. While there is more work to be done, as a nutraceutical manufacturer with products already on the market, we see these results as a robust leap towards better optimization of our CBD-enhanced products.”

PBIO has released two short videos (http://nnw.fm/2qOQV and http://nnw.fm/opQ3D) showing how its patented UST platform was able to process CBD plant oil into a water-soluble nanoemulsion. When the UST-processed CBD oil was added to different liquids – such as a soft drink, a sports drink and a beer – the nanoemulsified CBD oil completely dissolved in each liquid.

For many oil-based products, the ability to create nanoemulsions can improve the products’ absorption, medicinal benefits, visual appearance and sensory presentation, Dr. Bradford A. Young, chief commercial officer of Pressure BioSciences, stated in a news release introducing the videos (http://nnw.fm/iD61P).

“The potential for the UST platform to impact the CBD industry is promising, with the total cannabinoid market expected to hit $22 billion by 2022 with CBD oil-based supplements being the cornerstone of this market,” Young said (http://nnw.fm/dd6Aw). “More importantly, while CBD is an attractive opportunity for our proprietary UST platform, we believe that the nutraceuticals, topicals and cosmetics, and food and beverage markets as mentioned could be 10-50 times larger. We will be addressing these additional market opportunities in parallel with our efforts in CBD.”

Cannabidiol (CBD), is a naturally occurring compound found in cannabis and hemp plants that is non-psychoactive. CBD can now be found in a dizzying variety of CBD-infused products, including edibles, lotions, capsules, medications and other health and wellness products, as The New York Times reported in an article reviewing CBD’s history and future potential (http://nnw.fm/5WzUh).

Dr. Keith Warriner, professor of food science at the University of Guelph (Toronto), and a recognized expert in the cannabis industry, said that PBIO’s UST platform is a significant achievement.

“The data released today on UST-generated nanoemulsions of CBD oil are very impressive. Creating nanoemulsions of CBD oil with full preservation of CBD throughout the process, while not generating impurities, remains a significant challenge in the industry. These data indicate that UST can achieve that goal, thereby offering great promise to the future,” Warriner stated in February.

PBIO believes that its proprietary Ultra Shear Technology can help a diverse variety of customers to develop a vast array of new and beneficial products spanning multiple large markets including CBD and nutraceuticals, cosmetics and topicals, food and beverages, drug delivery and more, Young concluded.

For more information, visit the company’s website at www.PressureBioSciences.com

NOTE TO INVESTORS: The latest news and updates relating to PBIO are available in the company’s newsroom at http://nnw.fm/PBIO

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